HCN3 Antibody (S141-28) [Janelia Fluor® 646]

Product Discontinued

HCN3 Antibody (S141-28) [Janelia Fluor® 646] Summary

• Immunogen: Fusion protein amino acids 660-779 (C terminus) of mouse HCN3
• Localization: Membrane
• Specificity: Detects approx 90kDa. No cross-reactivity against other HCNs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: HCN3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for HCN3 Antibody (S141-28) [Janelia Fluor® 646]

• HCN3
• hyperpolarization activated cyclic nucleotide-gated potassium channel 3
• KIAA1535
• KIAA1535MGC131493
• potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3

Background

FUNCTION: Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. SUBUNIT: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. DOMAIN: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HCN3