Human Granzyme M ELISA Kit (Colorimetric)

ELISA: Human Granzyme M ELISA Kit (Colorimetric) [NBP3-31841] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma, tissue homogenates and other biological fluids
• Standard Curve Range: 15.625 - 1000 pg/mL (example only; lot dependent)
• Sensitivity: 5.9 pg/mL (example only; lot dependent)

Human Granzyme M ELISA Kit (Colorimetric) Summary

• Description: Assay Length: 4.5 hours
• Standard Curve Range: 15.625 - 1000 pg/mL (example only; lot dependent)
• Sensitivity: 5.9 pg/mL (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Inter-Assay: %CV < 12 (example only; lot dependent)
• Intra-Assay: %CV < 10 (example only; lot dependent)
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: GZMM

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Granzyme M ELISA Kit (Colorimetric)

• EC 3.4.21
• EC 3.4.21.-
• granzyme M (lymphocyte met-ase 1)
• granzyme M
• Hu-Met-1
• LMET1
• lymphocyte met-ase 1
• Met-1 serine protease
• MET1met-ase
• Met-ase
• Natural killer cell granular protease

Background

The GZMM gene encodes a 257 amino acid long, 27 kDA granzyme M protein that cleaves peptide substrates after methionine, leucine, and norleucine. In doing so, it encourages caspase activation and apoptosis of target cells. GZMM has been investigated for its role in arrhythmogenic right ventricular dysplasia as it participates in the immune system, alternative complement activation, and granzyme pathways. It is known to interact with genes CASP3, DFFA, EZR, NPM1, and PAK2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: GZMM