GPR35 Antibody - BSA Free

Immunohistochemistry-Paraffin: GPR35 Antibody [NLS2] - Analysis of anti-GPR35 antibody with human pancreas at 5 ug/ml.

• Reactivity: Hu, Pm
• Applications: IHC, IHC-P, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

GPR35 Antibody - BSA Free Summary

• Immunogen: Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human GPR35.
• Epitope: 3rd cytoplasmic domain
• Localization: Integral membrane protein
• Specificity: Human GPR35. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Primate (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GPR35
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry 1:10 - 1:500
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 - 9 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (95%), Monkey (84%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Notes

Product can be stored undiluted at 4C for up to 1 month.

Alternate Names for GPR35 Antibody - BSA Free

• G protein-coupled receptor 35
• GPR35
• G-protein coupled receptor 35
• KYNA receptor
• Kynurenic acid receptor

Background

GPR35 is an Orphan-A GPCR with an unknown ligand. GPR35 expression was reported only in rat intestine (O'Dowd et al., 1998) by Northern hybridization; however, another study showed that GPR35 is expressed widely, including pancreatic islets and skeletal muscle, with higher levels in adult lung, small intestine, colon, and stomach. ESTs have been isolated from human fetal lung/testis/B-cell, colon (normal, cancer, and Crohn's disease), breast cancer, pancreatic cancer, and leukemia libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPR35
• Entrez:
  • 2859(Human)
• Uniprot:
  • Q9HC97()