GPR35 Antibody

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Immunohistochemistry-Paraffin: GPR35 Antibody [NLS2] - Analysis of anti-GPR35 antibody with human pancreas at 5 ug/ml.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications IHC-P, ICC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

GPR35 Antibody Summary

Immunogen
Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human GPR35.
Localization
Integral membrane protein
Specificity
Human GPR35. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GPR35
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 5 - 9 ug/ml
  • Immunocytochemistry 1:10 - 1:500

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (95%), Monkey (84%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GPR35 Antibody

  • G protein-coupled receptor 35
  • GPR35
  • G-protein coupled receptor 35
  • KYNA receptor
  • Kynurenic acid receptor

Background

GPR35 is an Orphan-A GPCR with an unknown ligand. GPR35 expression was reported only in rat intestine (O'Dowd et al., 1998) by Northern hybridization; however, another study showed that GPR35 is expressed widely, including pancreatic islets and skeletal muscle, with higher levels in adult lung, small intestine, colon, and stomach. ESTs have been isolated from human fetal lung/testis/B-cell, colon (normal, cancer, and Crohn's disease), breast cancer, pancreatic cancer, and leukemia libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GPR35
Entrez
Uniprot