GPR12 Antibody (584940) [mFluor Violet 610 SE]

• Reactivity: Hu
• Applications: Flow, IHC
• Clone: 584940
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

GPR12 Antibody (584940) [mFluor Violet 610 SE] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human GPR12
  Met1-Val334
  Accession # P47775
• Specificity: Detects human GPR12 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GPR12

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for GPR12 Antibody (584940) [mFluor Violet 610 SE]

• FLJ18149
• FLJ97704
• G protein-coupled receptor 12
• GPCR12
• GPCR21
• GPR12
• G-protein coupled receptor 12
• MGC138349
• MGC138351

Background

GPCR GPR12 is a G protein coupled receptor. A variety of extracellular signals are transmitted into cells through integral membrane receptors coupled to heterotrimeric G proteins. Such G protein coupled receptors are critical for the normal functions of many cell types: neurons, endocrine cells, cardiac and smooth muscle cells, and sensory cells for detection of light, taste, and smell. Both activating and loss of function mutations in G protein coupled receptors have been found as the cause of human diseases. The GPR12 gene is located on human chromosome 13q12. GPR12 expression has been reported primarily in the central nervous system. Rat transcripts have been identified at low levels in testis and pituitary gland. ESTs have been isolated from human brain and eye libraries, as well as mouse brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPR12