GPR12 Products

Description

GPCR GPR12 is a G protein coupled receptor. A variety of extracellular signals are transmitted into cells through integral membrane receptors coupled to heterotrimeric G proteins. Such G protein coupled receptors are critical for the normal functions of many cell types: neurons, endocrine cells, cardiac and smooth muscle cells, and sensory cells for detection of light, taste, and smell. Both activating and loss of function mutations in G protein coupled receptors have been found as the cause of human diseases. The GPR12 gene is located on human chromosome 13q12. GPR12 expression has been reported primarily in the central nervous system. Rat transcripts have been identified at low levels in testis and pituitary gland. ESTs have been isolated from human brain and eye libraries, as well as mouse brain.

Bioinformatics

Entrez	2835 Human
Uniprot	P47775 Human NP_005279 Human NP_005279.1 Human
Product By Gene ID	2835
Alternate Names	GPCR12 G-protein coupled receptor 12 FLJ97704 FLJ18149 MGC138351 GPCR21 MGC138349 G protein-coupled receptor 12

Diseases related to GPR12

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Pertussis
Nervousness
Pituitary Diseases
Neuroblastoma
Cell Transformation, Neoplastic
Dyslipidemias
Stenosis
Steatohepatitis
Nervous System Disorder
Steatosis
Infertility
Female Infertility
Physiological Stress
Metabolic Diseases
Tumor Angiogenesis
Malignant Neoplasms
Neuritis
Obesity
Malignant Neoplasm Of Ovary

Pathways for GPR12

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Cell Proliferation
Oocyte Maturation
Prophase
Meiosis
Endocytosis
Cell Cycle
Receptor-mediated Endocytosis
Regulation Of Energy Homeostasis
Smooth Muscle Cell Proliferation
Muscle Cell Proliferation
Diplotene
Meiotic Prophase I
Brain Development
Energy Homeostasis
Localization
Regeneration
Regulation Of Cell Proliferation
Cell Differentiation
Angiogenesis
Oogenesis

Research Areas for GPR12

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GPCR

PTMs for GPR12

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Phosphorylation

Bioinformatics Tool for GPR12

Discover related pathways, diseases and genes to GPR12. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.