GPR116 Antibody

Immunohistochemistry-Paraffin: GPR116 Antibody [NLS1513] - Brain, substantia nigra

Immunohistochemistry-Paraffin: GPR116 Antibody [NLS1513] - Analysis of anti-GPR116 antibody with brain, neuron at 2 ug/ ml.

Immunohistochemistry-Paraffin: GPR116 Antibody [NLS1513] - Analysis of anti-GPR116 antibody with human adrenal, pheochromocytoma.

Immunohistochemistry-Paraffin: GPR116 Antibody [NLS1513] - Anti-GPR116 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: GPR116 Antibody [NLS1513] - Anti-GPR116 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Discontinued

GPR116 Antibody Summary

• Immunogen: Synthetic 19 amino acid peptide from N-terminal extracellular domain of human GPR116.
• Epitope: N-terminal extracellular domain of human
• Specificity: Human GPR116. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Primate (95%), Monkey (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADGRF5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 2 - 4 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (95%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GPR116 Antibody

• FLJ90640
• G protein-coupled receptor 116
• GPR116
• Ig-Hepta homolog
• KIAA0758DKFZp564O1923
• KPG_001
• probable G-protein coupled receptor 116

Background

GPR116/KIAA0758 is an Orphan-B GPCR with an unknown ligand. GPR116 has two immunoglobulin-like repeats and a SEA box. RT-PCR analysis from the KIAA database suggests that KIAA0758 is expressed in heart, kidney, lung and ovary. ESTs have been isolated from brain, breast, eye, heart, kidney, liver, liver/spleen, lung, nasopharyngeal, spleen, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GPR116 Antibody (NLS1513)(1)

Publication using NLS1513

• Massoner P, Kugler KG, Unterberger K et al. Characterization of Transcriptional Changes in ERG Rearrangement-Positive Prostate Cancer Identifies the Regulation of Metabolic Sensors Such as Neuropeptide Y. PLoS One 2013-01-01 [PMID: 23390522]

Bioinformatics

• Gene Symbol: ADGRF5
• Entrez:
  • 221395(Human)