GPR109B/HM74 Antibody

Images

 
Immunohistochemistry-Paraffin: GPR109B/HM74 Antibody [NLS180] - Anti-HCAR3 / GPR109B / HM74 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more
Immunohistochemistry-Paraffin: GPR109B/HM74 Antibody [NLS180] - Analysis of anti-GPR109B / HM74 antibody with transfection control.
Immunohistochemistry-Paraffin: GPR109B/HM74 Antibody [NLS180] - Analysis of anti-GPR109B / HM74 antibody with transfection positive.
Immunohistochemistry-Paraffin: GPR109B/HM74 Antibody [NLS180] - Analysis of anti-GPR109B / HM74 antibody with human adipocytes at 19 ug/ml.

Product Details

Summary
Reactivity Hu, Ca, Ha, Mu, Rt, Eq, GP, PmSpecies Glossary
Applications IHC-P, ICC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

GPR109B/HM74 Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR109B / HM74.
Localization
Multi-pass membrane protein
Specificity
Human GPR109B / HM74. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HCAR2 (100%), GPR81 (50%).
Predicted Species
Mouse (95%), Rat (90%), Primate (100%), Equine (95%), Guinea Pig (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HCAR3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 19 - 38 ug/ml
  • Immunocytochemistry 1:10 - 1:500

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Panda (100%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GPR109B/HM74 Antibody

  • G protein-coupled receptor 109B
  • GPR109B
  • G-protein coupled receptor 109B
  • G-protein coupled receptor HM74
  • G-protein coupled receptor HM74B
  • GTP-binding protein
  • HCA3
  • HCAR3
  • HM74
  • HM74B
  • HM74Puma-g
  • Niacin receptor 2
  • NIACR2
  • Nicotinic acid receptor 2
  • PUMAG
  • putative chemokine receptor

Background

HM74 is a Nicotinic Acid GPCR. HM74 expression has been reported in adipose and spleen, as well as lymphocytes and monocytes. ESTs have been isolated from adipose, blood, liver, liver/spleen, placenta, prostate, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HCAR3
Entrez