GPR109B/HM74 Antibody

Product Discontinued

GPR109B/HM74 Antibody Summary

• Immunogen: Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human GPR109B / HM74.
• Localization: Multi-pass membrane protein
• Specificity: Human GPR109B / HM74. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HCAR2 (100%), GPR81 (50%).
• Predicted Species: Mouse (95%), Rat (90%), Primate (100%), Equine (95%), Guinea Pig (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HCAR3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry 1:10 - 1:500
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 19 - 38 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GPR109B/HM74 Antibody

• G protein-coupled receptor 109B
• GPR109B
• G-protein coupled receptor 109B
• G-protein coupled receptor HM74
• G-protein coupled receptor HM74B
• GTP-binding protein
• HCA3
• HCAR3
• HM74
• HM74B
• HM74Puma-g
• Niacin receptor 2
• NIACR2
• Nicotinic acid receptor 2
• PUMAG
• putative chemokine receptor

Background

HM74 is a Nicotinic Acid GPCR. HM74 expression has been reported in adipose and spleen, as well as lymphocytes and monocytes. ESTs have been isolated from adipose, blood, liver, liver/spleen, placenta, prostate, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HCAR3
• Entrez:
  • 8843(Human)