GMDS Antibody (OTI2A1) [DyLight 550]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI2A1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 550

GMDS Antibody (OTI2A1) [DyLight 550] Summary

• Immunogen: Full length recombinant protein of human GMDS (NP_001491) produced in HEK293T cells.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: GMDS
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GMDS Antibody (OTI2A1) [DyLight 550]

• EC 4.2.1.47
• GDP-D-mannose dehydratase
• GDP-mannose 4,6-dehydratase
• GMDGDP-mannose 4,6 dehydratase
• SDR3E1
• short chain dehydrogenase/reductase family 3E, member 1

Background

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose,the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third stepsof the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX inhumans (MIM 137020).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GMDS