Species: Hu, Mu, Rt, Bv, RM, Xp
Applications: WB, IHC, KD
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose,the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third stepsof the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX inhumans (MIM 137020).(supplied by OMIM)
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
2762 |
Alternate Names |
- EC 4.2.1.47
- GDP-D-mannose dehydratase
- GDP-mannose 4,6-dehydratase
- GMDGDP-mannose 4,6 dehydratase
- SDR3E1
- short chain dehydrogenase/reductase family 3E, member 1
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Research Areas for GMDS
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Stem Cell Markers