Glycogen Phosphorylase BB/GPBB Antibody (6G5)

Product Discontinued

Glycogen Phosphorylase BB/GPBB Antibody (6G5) Summary

• Immunogen: Recombinant full length protein (Human).
• Specificity: Specific to the BB isoenzyme.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PYGB
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:100-1:2000
• Application Notes: Western Blot and Immunoassay It is recommended to use three-step assay, since signal is low in one-step and two-step assays.

Reactivity Notes

Cross-reacts with Human.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for Glycogen Phosphorylase BB/GPBB Antibody (6G5)

• Brain glycogen phosphorylase
• EC 2.4.1.1
• Glycogen phosphorylase B
• Glycogen phosphorylase brain form
• Glycogen Phosphorylase Isoenzyme BB
• GPBB
• MGC9213
• Phosphorylase glycogen brain
• PYGB

Background

This glycogen phosphorylase is found predominantly in the brain. Glycogen phosphorylase is a key enzyme of glycogenolysis, catalyzing the rate determining step in glycogen degradation. The activity of this enzyme is allosterically activated by AMP and alosterically inhibited by ATP, ADP, and glucose 6 phosphate.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PYGB
• Entrez:
  • 5834(Human)
• Uniprot:
  • P11216(Human)