GGCX Antibody

Images

 
Western Blot: GGCX Antibody [NBP2-16651] - Sample (30 ug of whole cell lysate) A: A431 B: HeLa C: HepG2 7. 5% SDS PAGE gel, diluted at 1:3000.
Immunocytochemistry/ Immunofluorescence: GGCX Antibody [NBP2-16651] - Confocal immunofluorescence analysis of methanol-fixed HeLa, using GGCX antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are labeled with ...read more
Immunohistochemistry-Paraffin: GGCX Antibody [NBP2-16651] - Immunohistochemical analysis of paraffin-embedded HBL435 xenograft, using antibody at 1:500 dilution.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, RM, ShSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

GGCX Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human GGCX. The exact sequence is proprietary.
Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein
Predicted Species
Mouse (95%), Rat (94%), Sheep (96%), Rhesus Macaque (99%), Bovine (96%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GGCX
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
88 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GGCX Antibody

  • EC 4.1.1.90
  • gamma-glutamyl carboxylaseFLJ26629
  • GC
  • Peptidyl-glutamate 4-carboxylase
  • Vitamin K gamma glutamyl carboxylase
  • vitamin K-dependent gamma-carboxylase
  • VKCFD1

Background

This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for GGCX Antibody (NBP2-16651) (0)

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Secondary Antibodies

 

Isotype Controls

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Calculators

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Bioinformatics

Gene Symbol GGCX
Uniprot