gamma-Synuclein Antibody

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Western Blot: Synuclein-gamma Antibody [NBP1-04361] - The recombinant synuclein family and the extracts of HT-29 (colon adenocarcinoma) cells were resolved by SDS-PAGE, transferred to PVDF membrane and probed with ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

gamma-Synuclein Antibody Summary

Immunogen
Recombinant human gamma-Synuclein purified from E. coli
Specificity
This is specific for gamma-synuclein and does not cross-react with alpha- and beta-synuclein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SNCG
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:100-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4) and 10% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for gamma-Synuclein Antibody

  • BCSG1
  • BCSG1PERSYN
  • Breast cancer-specific gene 1 protein
  • gamma-Synuclein
  • persyn
  • PRSN
  • SNCG
  • SRPRSN
  • Synoretin
  • synuclein, gamma (breast cancer-specific protein 1)
  • Synuclein-gamma

Background

Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. All synucleins have in common a highly conserved alpha-helical lipid-binding motif with similarity to the class-A2 lipid-binding domains of the exchangeable apolipoproteins. Although they are homologous, each synuclein is encoded by a different gene on chromosomes 4q21.3-q22. gamma-Synuclein (also called BCSG-1) is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SNCG
Entrez
Uniprot