Galectin-8 Antibody (210608) [PE]

• Reactivity: Hu
• Applications: WB
• Clone: 210608
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PE

Galectin-8 Antibody (210608) [PE] Summary

• Immunogen: E. coli-derived recombinant human Galectin-8
  Met1-Trp317
  Accession # O00214
• Specificity: Detects human Galectin-8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Galectin-1, -2, or -7 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: LGALS8
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for Galectin-8 Antibody (210608) [PE]

• GAL8
• Gal-8
• galectin 8
• Galectin8
• Galectin-8
• galectin-8g
• lectin, galactoside-binding, soluble, 8
• LGALS8
• PCTA1
• PCTA-1Po66 carbohydrate-binding protein
• Po66 carbohydrate binding protein
• Po66-CBP
• Prostate carcinoma tumor antigen 1

Background

Several proteins have been identified as specific markers of prostate cancer, and they may be useful as diagnostic indicators. PSA, prostate specific antigen, is the classical indicator for transformed prostate tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia prostate. Galectin-8, also known as prostate-specific membrane antigen (PCTA-1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cellmatrix interactions in a manner similar to the selectin subgroup of C-type lectins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LGALS8