FUBI/MNSF beta/FAU Antibody (861504) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clone: 861504
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 594

FUBI/MNSF beta/FAU Antibody (861504) [Alexa Fluor® 594] Summary

• Immunogen: E.coli-derived recombinant human FUBI/MNSFβ
  Met1-Gly74
  Accession # P35544
• Specificity: Detects human FUBI in direct ELISAs.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FUBI/MNSF beta/FAU Antibody (861504) [Alexa Fluor® 594]

• 40S Ribosomal Protein S30
• asr1
• FAU
• FAU1
• FAU-encoded ubiquitin-like protein
• FBR-MuSV-associated ubiquitously expressed
• Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
• Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed(fox derived)
• FLJ22986
• Fub1
• FUBI
• MNSFbeta
• monoclonal nonspecific suppressor factor beta
• ribosomal protein S30
• RPS30
• S30
• ubiquitin-like protein fubi and ribosomal protein S30
• ubiquitin-like-S30 fusion protein

Background

The ubiquitin-like protein FUBI/ MNSF beta (Monoclonal Nonspecific Suppressor Factor Beta) is encoded by the FAU gene, and is translated as a pro-form consisting of FUBI fused to the ribosomal S30 protein. S30 is cleaved in a post-translational reaction, releasing the mature 74 amino acid FUBI/MNSF beta protein. FUBI has a
C-terminal gly-gly motif common to many ubiquitin-like proteins.  FUBI/ MNSF beta conjugation to Bcl-G has been shown to regulate the ERK1/2-MAPK cascade in macrophage cell lines, and may be implicated in TLR4-mediated signal transduction. Conjugation to endophilin II regulates dectin-1-mediated phagocytosis and inflammatory responses, and may be implicated in TLR2 signaling pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.