FFAR1/GPR40 Antibody

Images

 
Western Blot: FFAR1/GPR40 Antibody [NBP1-00860] - Analysis of FFAR1/GPR40 pAb at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate
Western Blot: FFAR1/GPR40 Antibody [NBP1-00860] - Extracts from COS-7 cells treated with forskolin 40nM 30'

Product Details

Summary
Product Discontinued
View other related FFAR1/GPR40 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-00860
    • Availability
      Product Discontinued

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FFAR1/GPR40 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 201-250 of Human GPR40.
Clonality
Polyclonal
Host
Rabbit
Gene
FFAR1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
Theoretical MW
26 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for FFAR1/GPR40 Antibody

  • FFA1
  • FFAR1
  • free fatty acid receptor 1
  • G protein-coupled receptor 40
  • GPCR40
  • GPR40
  • GPR40FFA1R
  • G-protein coupled receptor 40

Background

G protein coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G proteincoupled receptor 40 (GPR40) functions as a cell-surface receptor for longchain free fatty acids (FFAs). FFAs provide an important energy source, but also function as signaling molecules in various pathways, notably the process of insulin secretion. In pancreatic tissue, the interaction of long chain FFAs with GPR40 amplifies glucose-stimulated insulin secretion from beta cells, suggesting a possible role for GPR40 in the treatment of diabetes associated with insulin-deficiency. Specifically, the Arg211His polymorphism in the GPR40 gene may contribute to the variation of insulin secretory capacity in Japanese men. Also, GPR40 may be involved in the control of breast cancer cell growth by fatty acids and, therefore, provide a link between fat and cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Additional FFAR1/GPR40 Products

Bioinformatics Tool for FFAR1/GPR40 Antibody (NBP1-00860)

Discover related pathways, diseases and genes to FFAR1/GPR40 Antibody (NBP1-00860). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for FFAR1/GPR40 Antibody (NBP1-00860)

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Pathways for FFAR1/GPR40 Antibody (NBP1-00860)

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PTMs for FFAR1/GPR40 Antibody (NBP1-00860)

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Bioinformatics

Gene Symbol FFAR1
Entrez
Uniprot