Human Free Fatty Acid Receptor 1 (FFAR-1), also known as GPR40, is a class A G-protein coupled receptor (GPCR) for medium and long chain saturated and unsaturated fatty acids encoded by the FFAR1 gene. FFAR-1 is expressed in pancreas and it plays an important role in glucose homeostasis acting as a nutrient sensor. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1).
| Uniprot | Human |
| Product By Gene ID | 2864 |
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