FCRL4/FcRH4/IRTA1 Antibody (580810) [Unconjugated]

RPMI 8226 human multiple myeloma cell line was stained with Mouse Anti-Human FCRL4/FcRH4 Monoclonal Antibody (Catalog # MAB24262, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 580810
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

FCRL4/FcRH4/IRTA1 Antibody (580810) [Unconjugated] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human FCRL4/FcRH4
  Gln16-Asp385
  Accession # NP_112572
• Specificity: Detects human FCRL4/FcRH4 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human FCRL1 is observed.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCRL4
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FCRL4/FcRH4/IRTA1 Antibody (580810) [Unconjugated]

• CD307d antigen
• CD307d
• Fc receptor homolog 4
• Fc receptor-like 4
• FcRH4
• FCRH4Fc receptor-like protein 4
• FCRL4
• FcR-like protein 4
• hIFGP2
• IFGP family protein 2
• IFGP2
• IGFP2
• Immune receptor translocation-associated protein 1
• immunoglobulin superfamily Fc receptor, gp42
• immunoglobulin superfamily receptor translocation associated 1
• IRTA1
• IRTA1MGC150523
• MGC150522

Background

Fc receptor-like 4 (FCRL4), also known as FcRH4 and IRTA1, is an Ig superfamily transmembrane protein that shares sequence homology with the classical Fc receptors. FCRL4 is preferentially expressed in B cells and contains three potential ITIM motifs in its cytoplasmic domain. The gene for FCRL4 is localized to the human chromosome 1q21‑23 region, a hotspot for translocation events.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCRL4
• Uniprot:
  • NP_112572()