FAT1 Antibody (FAT-1 3D7/1) Summary
Immunogen |
Cytoplasmic domain of drosophila Fat |
Localization |
Cell Membrane |
Predicted Species |
Chimpanzee (92%). Backed by our 100% Guarantee. |
Isotype |
IgM |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
FAT1 |
Purity |
IgM purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:100 - 1:2000
- Immunocytochemistry/Immunofluorescence 1:10 - 1:500
- Immunohistochemistry 1:10 - 1:500
- Western Blot 1:100 - 1:2000
|
Application Notes |
3-8% gradient gels and wet transfer techniques are recommended for the visualisation of Fat-1. |
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Rat (85%)
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.02% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
IgM purified |
Notes
Positive control(s): Wild type imaginal discs from third instar Drosophila larvae..
Alternate Names for FAT1 Antibody (FAT-1 3D7/1)
Background
The Drosophila FAT 1 gene does not belong to the classical cadherin gene family yet encodes a transmembrane protein containing 34 cadherin repeats in association with a number of other motifs. The Drosophila FAT locus encodes a tumor suppressor gene and recessive (loss-of-function) mutations lead to hyperplastic overgrowth of the imaginal discs, indicating that contact dependent cell interactions may play an important role in regulating growth and cell adhesion. This excessive cell proliferation occurs while maintaining normal epithelial organization and differentiation potential. Expressed in many epithelial and some endothelial and smooth muscle cells. Humans contain many homologs of FAT including FAT1, or hFAT
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu
Applications: IHC, WB
Species: Hu
Applications: IHC, IHC-P
Species: Hu
Applications: IHC, IHC-P, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: Flow, ICC/IF, IHC, IHC-P
Species: Hu
Applications: CyTOF-ready, ICC, ICFlow
Species: Hu
Applications: WB
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, KO, WB
Species: Hu, Mu
Applications: WB
Species: Hu
Applications: ICC, IP, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
Species: Mu, Rt
Applications: ICC, IHC, Simple Western, WB
Species: Hu
Applications: IHC, IHC-P
Species: Hu, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, WB
Species: Mu
Applications: IHC
Species: Ca, Hu, Mu, Rt, Ze
Applications: ChIP, IB, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KD, KO, Simple Western, WB
Publications for FAT1 Antibody (NB100-2693) (0)
There are no publications for FAT1 Antibody (NB100-2693).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for FAT1 Antibody (NB100-2693) (0)
There are no reviews for FAT1 Antibody (NB100-2693).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for FAT1 Antibody (NB100-2693) (0)
Secondary Antibodies
| |
Isotype Controls
|
Additional FAT1 Products
Bioinformatics Tool for FAT1 Antibody (NB100-2693)
Discover related pathways, diseases and genes to FAT1 Antibody (NB100-2693). Need help?
Read the
Bioinformatics Tool Guide for instructions on using this tool.
Diseases for FAT1 Antibody (NB100-2693)
Discover more about diseases related to FAT1 Antibody (NB100-2693).
| | Pathways for FAT1 Antibody (NB100-2693)
View related products by pathway.
|
PTMs for FAT1 Antibody (NB100-2693)
Learn more about PTMs related to FAT1 Antibody (NB100-2693).
| | Research Areas for FAT1 Antibody (NB100-2693)
Find related products by research area.
|
Blogs on FAT1