Recombinant Human FABP8/M-FABP/Myelin P2 Protein Protein

Product Discontinued

Recombinant Human FABP8/M-FABP/Myelin P2 Protein Protein Summary

• Description: An un-tagged recombinant protein corresponding to the amino acids 1-132 of Human FABP8/M-FABP/Myelin P2 Protein
  
  

  Source: E.coli

  Amino Acid Sequence: MSNKFLGTWK LVSSENFDDY MKALGVGLAT RKLGNLAKPT VIISKKGDII TIRTESTFKN EISFKLGQE FEETTADNRK TKSIVTLQRG SLNQVQRWDG KETTIKRKLV NGKMVAECKM KGVVCTRIYE KV

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: PMP2
• Purity: >95% pure by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 14.9 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 7.5), 2 mM EDTA, 1 mM DTT, 10% glycerol
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >95% pure by SDS-PAGE
• Reconstitution Instructions: Reconstitute with 50 ul of distilled water to a final concentration is 1.0 mg/ml.

Alternate Names for Recombinant Human FABP8/M-FABP/Myelin P2 Protein Protein

• FABP8
• MFABP
• M-FABP
• MP2
• myelin P2 protein
• P2
• peripheral myelin protein 2FABP8
• PMP2

Background

PMP2 (Myelin P2 Protein) is a small basic protein found in peripheral nerve myelin and spinal cord myelin, belongs to a family of fatty acid binding proteins. Myelin P2 Protein partly decreases the inhibitory effect of T suppressors in the culture of immune lymph node cells. Recombinant Myelin P2 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for FABP8/M-FABP/Myelin P2 Protein Recombinant Protein (NBC1-18345)(1)

Publication using NBC1-18345

• Moalem-Taylor G, Baharuddin B, Bennett B et al. Immune dysregulation in patients with carpal tunnel syndrome Sci Rep 2017-08-15 [PMID: 28811623] (Human)
  
  Details:
  The myelin p2 protein was used to look at the IFN gamma response to myelin p2 stimulation of T cells.

Bioinformatics

• Gene Symbol: PMP2