Exosome component 1 Antibody

Western Blot: Exosome component 1 Antibody [H00051013-B02P] - Analysis of EXOSC1 expression in transfected 293T cell line by EXOSC1 polyclonal antibody. Lane 1: EXOSC1 transfected lysate(21.45 KDa). Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: Exosome component 1 Antibody [H00051013-B02P] - Analysis of purified antibody to EXOSC1 on HeLa cell. (antibody concentration 10 ug/ml)

Product Discontinued

Exosome component 1 Antibody Summary

• Immunogen: EXOSC1 (NP_057130.1, 1 a.a. - 195 a.a.) full-length human protein. MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETESQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
• Specificity: EXOSC1 - exosome component 1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: EXOSC1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Exosome component 1 Antibody

• CGI-108,3'-5' exoribonuclease CSL4 homolog
• CSL4 exosomal core protein homolog
• Csl4p
• CSL4p13
• exosomal core protein CSL4
• exosome component 1hCsl4p
• homolog of yeast exosomal core protein CSL4
• SKI4
• Ski4p

Background

This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EXOSC1
• Entrez:
  • 51013(Human)
• Uniprot:
  • NP_057130.1(Human)