Exosome component 1 Antibody (BM3)

Product Discontinued

Exosome component 1 Antibody (BM3) Summary

• Immunogen: A BALB/c mouse was immunized with nuclei from Pokeweed mitogen stimulated human peripheral blood lymphocytes.
• Specificity: p13 (BM3)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: EXOSC1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:5000-1:20000
  • Flow Cytometry
  • Immunohistochemistry 1:100
  • Western Blot 1:500-1:5000
• Application Notes: This antibody is suitable for flow cytometry and frozen section immunohistochemistry. The antibody does not stain tissue after paraffin treatment.
• Control:

  Exosome component 1 Overexpression Lysate

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Preservative: 0.01% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Exosome component 1 Antibody (BM3)

• CGI-108,3'-5' exoribonuclease CSL4 homolog
• CSL4 exosomal core protein homolog
• Csl4p
• CSL4p13
• exosomal core protein CSL4
• exosome component 1hCsl4p
• homolog of yeast exosomal core protein CSL4
• SKI4
• Ski4p

Background

p13 is a specific marker for human myeloid cells. Induction studies using HL-60 cells show that p13 is expressed during the early phases of myeloid differentiation. The mAb anti-p13 recognizes a nuclear antigen expressed in human granulocytes (98%) and monocytes (80%) residing in lymphoid and non-lymphoid tissues. BM3 is an early marker of myeloid differentiation. Immunoprecipitation experiments using S35 methionine labeled human myeloid leukemia cells show that BM3 identifies a 13 kDa protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EXOSC1
• Entrez:
  • 51013(Human)