EphB2 Antibody [PE]

• Reactivity: Hu, Mu
• Applications: WB, Flow, IHC, CyTOF-ready, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: PE

EphB2 Antibody [PE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse EphB2
  Val27-Lys548
  Accession # P54763
• Specificity: Detects mouse and human EphB2 in direct ELISAs and Western blots. In Western blots, approximately 5% cross-reactivity with recombinant rat (rr) EphB1, recombinant mouse (rm) EphA8, rmEphA6, rmEphB6, rmEphA3, rmEphA4, rmEphA7, rrEphA5, recombinant human EphA1, rmEphA2 and rmEphB3 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: EPHB2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for EphB2 Antibody [PE]

• CAPB
• Cek5
• Drt
• DRTEphB2
• EC 2.7.10
• EC 2.7.10.1
• EK5
• elk-related tyrosine kinase
• EPH receptor B2
• eph tyrosine kinase 3
• EphB2
• EPH-like kinase 5
• ephrin type-B receptor 2
• EPHT3MGC87492
• EPTH3
• Erk
• ERKHek5
• Hek5
• Nuk
• PCBC
• protein-tyrosine kinase HEK5
• Qek2
• Renal carcinoma antigen NY-REN-47
• Sek3
• Tyro5
• Tyrosine-protein kinase receptor EPH-3
• Tyrosine-protein kinase TYRO5

Background

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EPHB2