ELF3/ESE-1 Antibody (662516) [DyLight 550]

• Reactivity: Hu
• Applications: IHC
• Clone: 662516
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 550

ELF3/ESE-1 Antibody (662516) [DyLight 550] Summary

• Immunogen: E. coli-derived recombinant human ELF3
  Met1-Gly173
  Accession # P78245
• Specificity: Detects human ELF3 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human ELF5 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ELF3
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ELF3/ESE-1 Antibody (662516) [DyLight 550]

• E74-like factor 3 (ets domain transcription factor, epithelial-specific )
• E74-like factor 3
• ELF3
• Epithelial-restricted with serine box
• epithelial-specific)
• Epithelium-restricted Ets protein ESX
• Epithelium-specific Ets transcription factor 1
• EPR1
• EPR-1
• ERT
• ESX
• ets domain transcription factor, serine box (epithelial-specific)
• ETS-related transcription factor Elf-3
• JEN
• serine box

Background

ESE-1 (Epithelium-Specific Ets) is a novel, highly tissue-restricted member of the ets transcription factor/oncogene family, which has features distinct from those of any other ets-related factor. ESE-1 binds with high affinity to and transactivates the ets binding site in the promoter of the keratinocyte terminal differentiation marker gene, SPRR2A. ESE-1 is a critical regulator of epithelial cell differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ELF3