EIF3C Antibody

Product Discontinued

EIF3C Antibody Summary

• Immunogen: A synthetic peptide derived from a sequence between residues 1 and 50 of human eukaryotic translation initiation factor 3, subunit 8, 110kDa using the numbering given in Swiss-Prot entry Q99613 (GeneID 8663).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: EIF3C
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-10 ug/mg lysate
  • Western Blot 1:15000-1:30000
• Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Suggested working dilutions: * Western Blot: 1:15,000 - 1:30,000 Immunoprecipitation: 2 to 10 ug/mg lysate.** Histo/Cytochemistry: not tested *The investigator should determine the optimal working dilution for a specific application. **In initial testing, NB 100-510 appeared to be less efficient than NB 100-511 at IP.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for EIF3C Antibody

• cell migration-inducing protein 17
• eIF3 p110
• eIF3c
• EIF3CL
• eIF3-p110
• EIF3S8FLJ55450
• Eukaryotic translation initiation factor 3 subunit 8
• eukaryotic translation initiation factor 3 subunit C
• eukaryotic translation initiation factor 3, subunit 8 (110kD)
• eukaryotic translation initiation factor 3, subunit 8, 110kDa
• eukaryotic translation initiation factor 3, subunit C
• FLJ53378
• FLJ54400
• FLJ54404
• FLJ55750
• FLJ78287
• MGC189737
• MGC189744

Background

eIF3 is the largest of the mammalian translation initiation factors, and consists of at least twelve subunits ranging in mass from 35 to 170 kDa. eIF3 binds to the 40 S ribosome in an early step of translation initiation and promotes the binding of methionyl-tRNAi and mRNA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EIF3C
• Entrez:
  • 8663(Human)
  • 56347(Mouse)
  • 293484(Rat)
• Uniprot:
  • Q99613(Human)