dystrophia myotonica containing WD repeat motif Antibody

Images

 
Western Blot: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001] - Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody used at for WB at 0.4 ug/ml.
Immunohistochemistry: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-DMWD used at a dilution of 1:1,000 ( ...read more
Immunohistochemistry-Paraffin: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001] - FFPE section of human seminoma. Affinity purified rabbit anti-DMWD 1:250. DAB staining using Immunohistochemistry ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
   

Biological Strategies

     

Order Details

dystrophia myotonica containing WD repeat motif Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 609 and 659 of human dystrophia myotonica, WD repeat containing using the numbering given in entry NP_004934.1 (GeneID 1762).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DMWD
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for dystrophia myotonica containing WD repeat motif Antibody

  • D19S593E
  • DM9
  • DMRN9
  • DMR-N9
  • dystrophia myotonica WD repeat-containing protein
  • dystrophia myotonica, WD repeat containing
  • Dystrophia myotonica-containing WD repeat motif protein
  • dystrophia myotonica-containing WD repeat motif
  • gene59
  • Protein 59
  • Protein DMR-N9

Background

The gene that codes for DMWD (dystrophia myotonica WD-repeat containing protein) is located in the myotonic dystrophy (DM1) gene cluster on 19q. Mutations in the DM1 region affect DMPK (myotonic dystrophy protein kinase), a myosin kinase expressed in skeletal muscle, and are the cause of myotonic dystrophy, a form of muscular dystrophy characterized by wasting of the muscles and myotonia. DMWD is expressed ubiquitously and is most abundant in the testes and brain. Studies concerning its abundance and sub-cellular localization in brain tissue suggest that it may have a role in some of the mental symptoms associated with myotonic dystrophy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DMWD
Entrez
Uniprot