DUSP10 Antibody

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Western Blot: DUSP10 Antibody [H00011221-A01] - Analysis of DUSP10 expression in 293 (Cat # L026V1).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

DUSP10 Antibody Summary

Immunogen
DUSP10 (AAH20608, 1 a.a. ~ 141 a.a) full length recombinant protein with GST tag.MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVETVV
Specificity
DUSP10 - dual specificity phosphatase 10
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
DUSP10
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.
Publications
Read Publication using H00011221-A01.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
50% Glycerol
Preservative
No Preservative
Purity
Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DUSP10 Antibody

  • dual specificity phosphatase 10
  • dual specificity phosphatase MKP-5
  • EC 3.1.3.16
  • EC 3.1.3.48
  • MAP kinase phosphatase 5
  • Mitogen-activated protein kinase phosphatase 5
  • MKP-5dual specificity protein phosphatase 10
  • MKP5serine/threonine specific protein phosphatase

Background

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for DUSP10 Antibody (H00011221-A01)(1)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DUSP10
Entrez
OMIM
Uniprot