DUSP10 Products

Antibodies
DUSP10 Antibody
DUSP10 Antibody
NBP1-31001
Species: Hu, Bovine, Chicken, Primate, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DUSP10 Antibody
DUSP10 Antibody
NBP2-16235
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DUSP10 Antibody
DUSP10 Antibody
NBP1-82640
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
DUSP10 Overexpression Lysate ...
DUSP10 Overexpression Lysate (Native)
NBP2-05529
Applications: WB
DUSP10 Overexpression Lysate ...
DUSP10 Overexpression Lysate (Native)
NBL1-10045
Applications: WB
DUSP10 Overexpression Lysate ...
DUSP10 Overexpression Lysate (Native)
NBL1-10046
Applications: WB
Proteins
DUSP10 Recombinant Protein An ...
DUSP10 Recombinant Protein Antigen
NBP1-82640PEP
Species: Hu
Applications: AC
DUSP10 Recombinant Protein
DUSP10 Recombinant Protein
NBP1-78891
Species: Hu
Applications: PAGE
RNAi
DUSP10 RNAi
DUSP10 RNAi
H00011221-R03
Species: Hu
DUSP10 RNAi
DUSP10 RNAi
H00011221-R02
Species: Hu
DUSP10 RNAi
DUSP10 RNAi
H00011221-R01
Species: Hu

Description

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 11221
Alternate Names
  • EC 3.1.3.48
  • Mitogen-activated protein kinase phosphatase 5
  • EC 3.1.3.16
  • MAP kinase phosphatase 5
  • MKP5serine/threonine specific protein phosphatase
  • MKP-5dual specificity protein phosphatase 10
  • dual specificity phosphatase MKP-5
  • dual specificity phosphatase 10

Research Areas for DUSP10

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

PTMs for DUSP10

Learn more about PTMs related to DUSP10.

Phosphorylation
Dephosphorylation
Cleavage

Bioinformatics Tool for DUSP10

Discover related pathways, diseases and genes to DUSP10. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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