DPP10 Antibody (453601) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: WB
• Clone: 453601
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 350

DPP10 Antibody (453601) [Alexa Fluor® 350] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human DPP10 isoform 1
  Leu56-Glu796 (Pro340Ala)
  Accession # NP_065919
• Specificity: Detects human DPP10 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) DPPIV or rhDPP6 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DPP10 Antibody (453601) [Alexa Fluor® 350]

• dipeptidyl peptidase 10
• Dipeptidyl peptidase IV-related protein 3
• dipeptidyl peptidase like protein 2
• Dipeptidyl peptidase X
• Dipeptidyl peptidase-like protein 2
• dipeptidyl-peptidase 10 (non-functional)
• dipeptidyl-peptidase 10
• DPL2
• DPP X
• DPP10
• DPPY
• DPRP3
• DPRP-3
• DPRP3dipeptidylpeptidase 10
• inactive dipeptidyl peptidase 10
• KIAA1492

Background

DPP10 (dipeptidyl peptidase 10; also DPPY, DPRP3 and DPL2) is a 91‑97 kDa member of the peptidase S9B family. It is a type II transmembrane glycoprotein principally expressed in neurons and T cells. Although it is a peptidase member, it has no catalytic activity. Instead, it assists in the membrane trafficking and functioning of Kv4 K⁺ channels. Human DPP10 is 796 amino acids (aa) in length. It contains a 34 aa cytoplasmic N‑terminus and a 741 aa extracellular domain (ECD) (aa 56‑796). Three potential isoforms exist, all involving aa substitutions limited to the first 20 amino acids. The ECD of human DPP10 shares 89% aa sequence identity with mouse DPP10 ECD.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.