DOG1/TMEM16A Antibody (SPM580) [Alexa Fluor® 647]


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Product Details

Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Alexa Fluor 647

Order Details

DOG1/TMEM16A Antibody (SPM580) [Alexa Fluor® 647] Summary

Recombinant human DOG1/TMEM16A protein
Cell Surface and Cytoplasm
Gastrointestinal Stromal Tumor Marker
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GISTs), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GISTs, including all c-kit negative GISTs. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GISTs is nearly identical: 94.4% vs. 94.7%.
IgG1 Kappa
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Protein A or G purified


Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DOG1/TMEM16A Antibody (SPM580) [Alexa Fluor® 647]

  • ANO1
  • anoctamin 1
  • DOG1
  • ORAOV2
  • TAOS2
  • TMEM16A


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34812AF350
Alexa Fluor 405 NBP2-34812AF405
Alexa Fluor 488 NBP2-34812AF488
Alexa Fluor 532 NBP2-34812AF532
Alexa Fluor 594 NBP2-34812AF594
Alexa Fluor 647 NBP2-34812AF647
Alexa Fluor 700 NBP2-34812AF700
Alexa Fluor 750 NBP2-34812AF750
Biotin NBP2-34812B
DyLight 350 NBP2-34812UV
DyLight 405 NBP2-34812V
DyLight 488 NBP2-34812G
DyLight 550 NBP2-34812R
DyLight 594 NBP2-34812DL594
DyLight 650 NBP2-34812C
DyLight 680 NBP2-34812FR
DyLight 755 NBP2-34812IR
FITC NBP2-34812F
HRP NBP2-34812H
Janelia Fluor 549 NBP2-34812JF549
Janelia Fluor 646 NBP2-34812JF646

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Gene Symbol ANO1