Doc2-alpha Antibody [Janelia Fluor® 669]

• Reactivity: Hu, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Janelia Fluor 669

Doc2-alpha Antibody [Janelia Fluor® 669] Summary

• Immunogen: E. coli-derived recombinant human Doc2 alpha
  Met1-Lys114 (Gly48Ser)
  Accession # Q14183
• Specificity: Detects human and mouse Doc2 alpha in Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human Doc2 beta is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: DOC2A
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Doc2-alpha Antibody [Janelia Fluor® 669]

• Doc2 alpha
• Doc2
• DOC2A
• doc2-alpha
• double C2-like domain-containing protein alpha
• double C2-like domains, alpha

Background

There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which containtwo C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with theunrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to beinvolved in Ca(2+)-dependent neurotransmitter release. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DOC2A