Western Blot: DMP-1 Antibody [NBP1-45525] - Odonto/osteogenic differentiation in canonical NF-kB-inhibited SCAPs. The odonto/osteogenic protein levels of SCAPs in control, inhibitor, MM, and inhibitor + MM groups were ...read more
Western Blot: DMP-1 Antibody [NBP1-45525] - Analysis of DMP-1 in rat kidney tissue lysate.
Western Blot: DMP-1 Antibody [NBP1-45525] - Odonto/osteogenic differentiation in canonical NF-kB-activated SCAPs. Western blot analyses for the odonto/osteogenic proteins (BSP, OCN, RUNX2, OSX, DSP, OPN, DSP, and DMP-1) ...read more
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.2), 30% glycerol, 0.5% BSA
Alternate Names for DMP-1 Antibody
dentin matrix acidic phosphoprotein 1
dentin matrix acidic phosphoprotein
Dentin matrix protein 1
Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information go to www.P65Warnings.ca.gov.
Publications for DMP-1 Antibody (NBP1-45525)(6)
We have publications tested in 1 confirmed species: Human.
We have publications tested in 2 applications: ICC/IF, WB.
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Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.