DMP-1 Products

Antibodies
DMP-1 Antibody
DMP-1 Antibody
NBP1-89484
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
DMP-1 Antibody
DMP-1 Antibody
AF4386
Species: Mu
Applications: WB, IHC
Host: Sheep Polyclonal
DMP-1 Antibody
DMP-1 Antibody
NBP1-45525
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Proteins
DMP-1 Partial Recombinant Pro ...
DMP-1 Partial Recombinant Protein
H00001758-Q01
Species: Hu
Applications: WB, ELISA, PA
DMP-1 Recombinant Protein Ant ...
DMP-1 Recombinant Protein Antigen
NBP1-89484PEP
Species: Hu
Applications: AC
RNAi
DMP-1 RNAi
DMP-1 RNAi
H00001758-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 1758
Alternate Names
  • dentin matrix acidic phosphoprotein
  • ARHR
  • ARHP
  • DMP-1
  • Dentin matrix protein 1
  • dentin matrix acidic phosphoprotein 1

Bioinformatics Tool for DMP-1

Discover related pathways, diseases and genes to DMP-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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