Reactivity | Hu, Mu, RtSpecies Glossary |
Applications | WB, ELISA, IHC |
Clonality | Polyclonal |
Host | Rabbit |
Conjugate | DyLight 650 |
Immunogen | DIS3L2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human DIS3L2. The immunogen is located within amino acids 720 - 770 of DIS3L2. Amino Acid Squence: DTLQKQADHCNDRRMAS |
Specificity | DIS3L2 antibody is human, mouse and rat reactive. At least three isoforms of DIS3L2 are known to exist; this antibody will only detect the longest isoform. DIS3L2 is predicted to not cross-react with DIS3 or DIS3L. |
Isotype | IgG |
Clonality | Polyclonal |
Host | Rabbit |
Gene | DIS3L2 |
Purity | Peptide affinity purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Peptide affinity purified |
Secondary Antibodies |
Isotype Controls |
DIS3L2: Uridiylation Control of the Lin28-Let-7 Differentiation Pathway The Lin28-Let-7 stem cell differentiation regulatory pathway is responsible for maintaining stem cell pluripotency. Specifically, Lin28 causes uridiylation of the let-7 miRNA precursor, which prevents differentiation processing by Dicer. Instead, the ... Read full blog post. |
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Gene Symbol | DIS3L2 |