DCIR/CLEC4A Antibody (320507) [Phycoerythrin]

Mouse bone marrow-derived dendritic cells were stained with Rat Anti-Mouse DCIR/CLEC4A PE-conjugated Monoclonal Antibody (Catalog # FAB26171P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Mouse bone marrow cells were stained with Rat Anti-Mouse DCIR/CLEC4A PE-conjugated Monoclonal Antibody (Catalog # FAB26171P, filled histogram) or isotype control antibody (IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Mu
• Applications: Flow
• Clone: 320507
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Phycoerythrin

DCIR/CLEC4A Antibody (320507) [Phycoerythrin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse DCIR/CLEC4A isoform 1
  Gln70-Leu238
  Accession # Q9QZ15
• Specificity: Detects mouse DCIR/CLEC4A in direct ELISAs.
• Source: N/A
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: Clec4a2
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DCIR/CLEC4A Antibody (320507) [Phycoerythrin]

• CD367
• CLEC4A
• CLECSF6
• CLECSF6C-type lectin superfamily member 6
• C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6
• C-type lectin domain family 4 member A
• C-type lectin domain family 4, member A
• DCIR
• DCIRLLIR
• DDB27
• DDB27C-type lectin DDB27
• Dendritic cell immunoreceptor
• Lectin-like immunoreceptor
• LLIR

Background

DCIR (Dendritic Cell Immunoreceptor), also known as LLIR (Lectin-Like Immunoreceptor), is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM) in its cytoplasmic domain. Besides DC, DCIR is expressed on B cells, monocytes/macrophages and granulocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for DCIR/CLEC4A Antibody (FAB26171P)(1)

Publication using FAB26171P

• Long , Kristin, Whitmore , Alan C, Ferris , Martin T, Sempowski , Gregory, McGee , Charles, Trollinger , Bianca, Gunn , Bronwyn, Heise , Mark T Dendritic cell immunoreceptor regulates Chikungunya virus pathogenesis in mice. J Virol, 2013-03-13;87(10):5697-706. 2013-03-13 [PMID: 23487448] (Flow Cytometry, Mouse)

Bioinformatics

• Gene Symbol: Clec4a2
• Uniprot:
  • Q9QZ15()