DCIR/CLEC4A Antibody (111F8.04) [PE]

Flow Cytometry: DCIR/CLEC4A Antibody (111F8.04) [PE] [DDX0180PE] - Cell surface flow analysis of DCIR (shaded histogram) in human PBMCs using the monocyte population gated using forward and side scatter with DDX0180PE at 1ug/ml (A) and 3 ug/ml (B). Open histogram is isotype control.

Product Discontinued

DCIR/CLEC4A Antibody (111F8.04) [PE] Summary

• Immunogen: DCIR was used as immunogen.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CLEC4A
• Purity: Ion exchange chromatography

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
• Application Notes: Flow Cytometry, Immunocytochemistry/Immunofluorescence

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 100 ug antibody in 200 ul PBS
• Preservative: 0.05% Sodium Azide
• Purity: Ion exchange chromatography

Notes

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

Alternate Names for DCIR/CLEC4A Antibody (111F8.04) [PE]

• CD367
• CLEC4A
• CLECSF6
• CLECSF6C-type lectin superfamily member 6
• C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6
• C-type lectin domain family 4 member A
• C-type lectin domain family 4, member A
• DCIR
• DCIRLLIR
• DDB27
• DDB27C-type lectin DDB27
• Dendritic cell immunoreceptor
• Lectin-like immunoreceptor
• LLIR

Background

CLEC4A, also known as DCIR, is a member of the C-type lectin/C-type lectin-like (CTL/CTLD) domain superfamily. Members of the CTL/CTLD family have a variety of functions including cell adhesion, glycoprotein turnover and cell-cell signaling. CLEC4A may play a role in regulating immune reactivity. This protein is currently being studied for research on the following diseases and disorders: rheumatoid arthritis, osteoarthritis, pneumonia, influenza, eclampsia and melanoma. CLEC4A is known to have interactions with PTPN6.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for DCIR/CLEC4A Antibody (DDX0180PE)(1)

Publication using DDX0180PE

• Bates EE et al. APCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motif. J Immunol 1999-08-01 [PMID: 10438934]

Bioinformatics

• Gene Symbol: CLEC4A