Cysteine Conjugate beta-Lyase/CCBL1 Antibody [FITC]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: FITC

Cysteine Conjugate beta-Lyase/CCBL1 Antibody [FITC] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Cysteine Conjugate beta -Lyase/CCBL1
  Thr182-Leu422
  Accession # Q16773
• Specificity: Detects human, mouse, and rat Cysteine Conjugate beta -Lyase/CCBL1 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CCBL1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for Cysteine Conjugate beta-Lyase/CCBL1 Antibody [FITC]

• CCBL1
• Cysteine Conjugate betaLyase
• Cysteine Conjugate beta-Lyase
• cysteine conjugate-beta lyase, cytoplasmic
• cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K
• Cysteine-S-conjugate beta-lyase
• EC 2.6.1.64
• EC 2.6.1.7
• EC 4.4.1.13
• FLJ95217
• Glutamine Transaminase K
• glutamine-phenylpyruvate aminotransferase
• Glutamine--phenylpyruvate transaminase
• GTKMGC29624
• KAT1
• KATI
• KATIbeta-lysase, kidney
• Kyneurenine Aminotransferase I
• kyneurenine aminotransferase
• kyneurenine aminotransferase)
• Kynurenine aminotransferase I
• kynurenine--oxoglutarate transaminase 1
• Kynurenine--oxoglutarate transaminase I

Background

CCBL1 encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCBL1