CUGBP1/CELF1 Antibody (3B1) [DyLight 405]

Images

 
There are currently no images for CUGBP1/CELF1 Antibody (NB200-316V).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Pm, RbSpecies Glossary
Applications WB, Flow, ICC/IF, IHC-Fr, IHC-P
Clone
3B1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

CUGBP1/CELF1 Antibody (3B1) [DyLight 405] Summary

Immunogen
Full-length human CUGBP1 [UniProt# Q92879]
Localization
Nuclear
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CELF1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
This CUGBP1 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry frozen and paraffin embedded sections and Western Blot where a band is observed at ~50 kDa. Nuclear staining can be seen in ICC/IF. Immunoprecipitation and Gel Super Shift Assays were reported in scientific literature.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CUGBP1/CELF1 Antibody (3B1) [DyLight 405]

  • BRUNOL2
  • BRUNOL250 kDa nuclear polyadenylated RNA-binding protein
  • bruno-like 2
  • Bruno-like protein 2
  • CELF1
  • CUG RNA-binding protein
  • CUG triplet repeat, RNA binding protein 1
  • CUG triplet repeat, RNA-binding protein 1
  • CUG-BP- and ETR-3-like factor 1
  • CUGBP Elav-like family member 1
  • CUG-BP
  • CUGBP, Elav-like family member 1
  • CUGBP1
  • CUG-BP1
  • CUGBP1CUG triplet repeat RNA-binding protein 1
  • CUGBPCELF-1
  • D2Wsu101e
  • Deadenylation factor CUG-BP
  • EDEN-BP homolog
  • EDEN-BP
  • embryo deadenylation element binding protein
  • Embryo deadenylation element-binding protein homolog
  • HNAB50
  • NAB50
  • NAB50CUG-BP1
  • NAPOR
  • nuclear polyadenylated RNA-binding protein, 50-kD
  • RNA-binding protein BRUNOL-2

Background

CUGBP1 (CUG-binding protein 1) is a member of CELF (CUG-BP- and ETR-3-like factors) family of RNA-binding proteins that binds to a variety of mRNA cis-elements including UG-rich elements, GC-rich elements, GU-rich elements and AREs, and has been implicated in the regulation of mRNA alternative splicing as well as the control of mRNA translation and stability. CUGBP1 is ubiquitously expressed with localization in nucleus and cytoplasm as a component of an EIF2 complex which contains CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. CUGBP1 also associates with polysomes and interacts with HNRNPH1 and PARN. CUGBP1 was originally discovered as a protein which interacts with RNA CUG repeats that are expanded in patients with DM1 (myotonic dystrophy), which binds to 3'-untranslated region of the dystrophin myotonia protein kinase (DMPK) gene. However, CUGBP1 was later shown as multifunctional protein regulating many posttranscriptional processes including alternative splicing, deadenylation, mRNA decay, and translation. It has been involved in the processes of development (embryonic and cardiac), differentiation (skeletal muscle and adipose tissue), germ cell formation, tumorigenesis (breast cancer, leukemia etc) and deterioration of certain tumors as well.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB6967
Species: Hu
Applications: WB
NBP2-16035
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NB110-37256
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NB110-85519
Species: Hu, Mu
Applications: WB, ELISA, IHC, IP
NBP2-42632
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF
NBP1-89932
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP2-29463
Species: Hu, Mu, Rt, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
NBP2-12793
Species: Hu, Mu
Applications: WB, IP
NBP1-89933
Species: Hu
Applications: ICC/IF, IHC, IHC-P
H00023049-M02
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
NB200-412
Species: Hu, Mu, Rt, Ca
Applications: IA, S-ELISA
NBP2-46085
Species: Hu
Applications: WB, IHC
NBP1-31308
Species: Hu, Mu, Rt, Bv
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-87425
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-45731
Species: Hu, Ca, Mk
Applications: WB, IHC, IHC-P
NB600-101
Species: Hu, Mu, Rt, Bv, Ha, Pm
Applications: WB, Simple Western, B/N, DB, EM, ICC/IF, IHC, IHC-P, IP, PA
NBP1-31806
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-46179
Species: Hu
Applications: WB, IHC, IHC-P, IP
NB200-316V
Species: Hu, Mu, Rt, Po, Bv, Pm, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P

Publications for CUGBP1/CELF1 Antibody (NB200-316V) (0)

There are no publications for CUGBP1/CELF1 Antibody (NB200-316V).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for CUGBP1/CELF1 Antibody (NB200-316V) (0)

There are no reviews for CUGBP1/CELF1 Antibody (NB200-316V). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CUGBP1/CELF1 Antibody (NB200-316V) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB200-316APC
DyLight 350 Labeled NB200-316UV
DyLight 488 Labeled NB200-316G
DyLight 680 Labeled NB200-316FR
DyLight 755 Labeled NB200-316IR
FITC Labeled NB200-316F
PE Labeled NB200-316PE

Additional CUGBP1/CELF1 Products

Bioinformatics Tool for CUGBP1/CELF1 Antibody (NB200-316V)

Discover related pathways, diseases and genes to CUGBP1/CELF1 Antibody (NB200-316V). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CUGBP1/CELF1 Antibody (NB200-316V)

Discover more about diseases related to CUGBP1/CELF1 Antibody (NB200-316V).
 

Pathways for CUGBP1/CELF1 Antibody (NB200-316V)

View related products by pathway.

PTMs for CUGBP1/CELF1 Antibody (NB200-316V)

Learn more about PTMs related to CUGBP1/CELF1 Antibody (NB200-316V).
 

Research Areas for CUGBP1/CELF1 Antibody (NB200-316V)

Find related products by research area.

Blogs on CUGBP1/CELF1

There are no specific blogs for CUGBP1/CELF1, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our CUGBP1/CELF1 Antibody (3B1) [DyLight 405] and receive a gift card or discount.

Bioinformatics

Gene Symbol CELF1
Entrez