CSE1L/CAS/Exportin-2 Antibody (2F4) - Azide and BSA Free

Western Blot: CSE1L/CAS/Exportin-2 Antibody (2F4) [H00001434-M04] - Analysis of CSE1L expression in Hela S3 NE (Cat # L013V3).

Immunocytochemistry/Immunofluorescence: CSE1L/CAS/Exportin-2 Antibody (2F4) [H00001434-M04] - Analysis of monoclonal antibody to CSE1L on HeLa cell. Antibody concentration 10 ug/ml

Immunohistochemistry-Paraffin: CSE1L/CAS/Exportin-2 Antibody (2F4) [H00001434-M04] - Analysis of monoclonal antibody to CSE1L on formalin-fixed paraffin-embedded human testis. Antibody concentration 6 ug/ml

ELISA: CSE1L/CAS/Exportin-2 Antibody (2F4) [H00001434-M04] - Detection limit for recombinant GST tagged CSE1L is approximately 0.1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: 2F4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

CSE1L/CAS/Exportin-2 Antibody (2F4) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: CSE1L (NP_001307, 872 a.a. ~ 971 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LIGLFELPEDDTIPDEEHFIDIEDTPGYQTAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQGYLQAARVTLL
• Specificity: CSE1L - CSE1 chromosome segregation 1-like (yeast)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CSE1L
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500
• Application Notes: Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF, IHC-P and ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CSE1L/CAS/Exportin-2 Antibody (2F4) - Azide and BSA Free

• CAS
• CASMGC117283
• Cellular apoptosis susceptibility protein
• chromosome segregation 1 (yeast homolog)-like
• Chromosome segregation 1-like protein
• CSE1 chromosome segregation 1-like (yeast)
• CSE1
• CSE1L
• Exp2
• exportin-2
• Importin-alpha re-exporter
• MGC130037
• XPO2
• XPO2MGC130036

Background

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CSE1L
• Entrez:
  • 1434(Human)
• OMIM:
  • 601342(Human)
• Uniprot:
  • NP_001307(Human)