This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for CSE1L/CAS/Exportin-2 Antibody (2C10)
Cellular apoptosis susceptibility protein
chromosome segregation 1 (yeast homolog)-like
Chromosome segregation 1-like protein
CSE1 chromosome segregation 1-like (yeast)
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.