Recombinant Human CRYGD Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human CRYGD Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-174 of Human CRYGD

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGKITLYEDR GFQGRHYECS SDHPNLQPYL SRCNSARVDS GCWMLYEQPN YSGLQYFLRR GDYADHQQWM GLSDSVRSCR LIPHSGSHRI RLYEREDYRG QMIEFTEDCS CLQDRFRFNE IHSLNVLEGS WVLYELSNYR GRQYLLMPGD YRRYQDWGAT NARVGSLRRV IDFS

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CRYGD
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
22.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 10% glycerol, 200mM NaCl
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human CRYGD Protein

  • CACA
  • CCA3
  • CCP
  • CRYG4gamma crystallin 4
  • cry-g-D
  • crystallin, gamma D
  • Gamma-crystallin 4
  • gamma-crystallin D
  • gamma-D-crystallin

Background

CRYGD belongs to the beta/gamma-crystallin family. Crystallins are the dominant structural components of the vertebrate eye lens. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Gamma-crystallins have been involved in cataract formation. Defects in CRYGD are a cause of cataract autosomal dominant (ADC), cataract congenital non-nuclear polymorphic autosomal dominant (CCP), cataract congenital cerulean type 3 (CCA3) and cataract crystalline aculeiform (CACA). Recombinant human CRYGD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for CRYGD Protein (NBP1-72428) (0)

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FAQs for CRYGD Protein (NBP1-72428). (Showing 1 - 1 of 1 FAQ).

  1. Is rhCRYGD soluble in PBS?
    • This product comes in liquid in 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 10% glycerol, 200mM NaCl.

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Bioinformatics

Gene Symbol CRYGD