COQ3 Antibody - Azide and BSA Free

Western Blot: COQ3 Antibody [H00051805-B01P] - Analysis of COQ3 expression in HeLa.

Immunohistochemistry-Paraffin: COQ3 Antibody [H00051805-B01P] - Analysis of purified antibody to COQ3 on formalin-fixed paraffin-embedded human testis. (antibody concentration 3 ug/ml)

Western Blot: COQ3 Antibody [H00051805-B01P] - Analysis of COQ3 expression in transfected 293T cell line by COQ3 polyclonal antibody. Lane 1: COQ3 transfected lysate(40.59 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

COQ3 Antibody - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse COQ3 Antibody - Azide and BSA Free (H00051805-B01P) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: COQ3 (AAH63463.1, 1 a.a. - 369 a.a.) full-length human protein. MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIWFKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQIAGIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAHAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
• Specificity: COQ3 - coenzyme Q3 homolog, methyltransferase (yeast),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: COQ3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. Has also been used for immunohistochemistry (paraffin).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for COQ3 Antibody - Azide and BSA Free

• 3-demethylubiquinone-10 3-methyltransferase
• bA9819.1
• coenzyme Q3 homolog, methyltransferase (S. cerevisiae)
• coenzyme Q3 homolog, methyltransferase (yeast)
• DHHB methyltransferase
• DHHBMT
• DHHB-MT
• DHHBMTASE
• DHHB-MTase
• Dihydroxyhexaprenylbenzoate methyltransferase
• EC 2.1.1
• EC 2.1.1.114
• EC 2.1.1.64
• hexaprenyldihydroxybenzoate methyltransferase, mitochondrial3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase
• methyltransferase COQ3
• UG0215E05

Background

Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: COQ3
• Entrez:
  • 51805(Human)
• Uniprot:
  • AAH63463.1(Human)