COPS8 Antibody [FITC]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: FITC

COPS8 Antibody [FITC] Summary

• Immunogen: Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human CSN8. The immunogen is located within the last 50 amino acids of CSN8. Amino Acid Squence: PLSEPAPVPPIPNEQ
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: COPS8
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Alternate Names for COPS8 Antibody [FITC]

• COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
• COP9 homolog
• COP9 signalosome complex subunit 8
• COP9
• CSN8JAB1-containing signalosome subunit 8
• hCOP9
• MGC1297
• MMMEP
• SGN8MGC43256
• Signalosome subunit 8

Background

COPS8 is encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: COPS8