Complement Component C9 Antibody (887025) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: WB
• Clone: 887025
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

Complement Component C9 Antibody (887025) [Alexa Fluor® 647] Summary

• Immunogen: HEK293 human embryonic kidney cell line transfected with human Complement Component C9
  Met1-Lys559
  Accession # P02748
• Specificity: Detects human Complement Component C9 in ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Complement Component C9 Antibody (887025) [Alexa Fluor® 647]

• complement component 9
• Complement Component C9

Background

Complement Component 9 (C9) is a 65-70 kDa protein of the complement membrane attack complex (C5b-9) that binds C5b-8, polymerizes, and forms pores upon activation of the complement cascade. Mature human C9 shares 60% and 66% amino acid sequence identity with mouse and rat C9, respectively. It may be proteolytically cleaved by thrombin into a 28-34 kDa cysteine-rich, mannosylated soluble C9a subunit, and a 37-38 kDa membrane-anchored N-glycosylated C9b. These fragments are also able to polymerize.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.