Human Coagulation Factor XI ELISA Kit (Colorimetric)

ELISA: Human Coagulation Factor XI ELISA Kit (Colorimetric) [NBP2-60626]

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, Plasma, Cell Culture
• Standard Curve Range: 1.562 - 50 ng/mL; 0.194 - 6.2 mIU/mL (example only; lot dependent)
• Sensitivity: 1.5 ng/ml (example only; lot dependent)

Human Coagulation Factor XI ELISA Kit (Colorimetric) Summary

• Description: This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
• Standard Curve Range: 1.562 - 50 ng/mL; 0.194 - 6.2 mIU/mL (example only; lot dependent)
• Sensitivity: 1.5 ng/ml (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Inter-Assay: CV% < 7.10% (example only; lot dependent)
• Intra-Assay: CV% < 5.10% (example only; lot dependent)
• Spike Recovery: 97.50% (example only; lot dependent)
• Kit Type: ELISA Kit (Colorimetric)
• Gene: F11

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Coagulation Factor XI ELISA Kit (Colorimetric)

• Coagulation Factor XI
• EC 3.4.21
• EC 3.4.21.27
• FXIPlasma thromboplastin antecedent
• MGC141891
• PTA

Background

Factor XI encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for Coagulation Factor XI ELISA Kit (NBP2-60626)(1)

Publication using NBP2-60626

• Fang, Y;Liu, Y;Chen, L;Wang, J;Zhang, J;Zhang, H;Tian, S;Zhang, A;Zhang, J;Zhang, JH;Wang, X;Yu, J;Chen, S; Cerebrospinal fluid markers of neuroinflammation and coagulation in severe cerebral edema and chronic hydrocephalus after subarachnoid hemorrhage: a prospective study Journal of neuroinflammation 2024-09-27 [PMID: 39334416]

Bioinformatics

• Gene Symbol: F11