Human Coagulation Factor XI ELISA Kit (Colorimetric)

ELISA: Human Coagulation Factor XI ELISA Kit (Colorimetric) [NBP2-60626]

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, Plasma, Cell Culture
• Standard Curve Range: 1.562 - 50 ng/mL; 0.194 - 6.2 mIU/mL (example only; lot dependent)
• Sensitivity: 1.5 ng/ml (example only; lot dependent)

Human Coagulation Factor XI ELISA Kit (Colorimetric) Summary

• Description: This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
• Standard Curve Range: 1.562 - 50 ng/mL; 0.194 - 6.2 mIU/mL (example only; lot dependent)
• Sensitivity: 1.5 ng/ml (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Inter-Assay: CV% < 7.10% (example only; lot dependent)
• Intra-Assay: CV% < 5.10% (example only; lot dependent)
• Spike Recovery: 97.50% (example only; lot dependent)
• Kit Type: ELISA Kit (Colorimetric)
• Gene: F11

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Coagulation Factor XI ELISA Kit (Colorimetric)

• Coagulation Factor XI
• EC 3.4.21
• EC 3.4.21.27
• FXIPlasma thromboplastin antecedent
• MGC141891
• PTA

Background

Factor XI encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for Coagulation Factor XI ELISA Kit (NBP2-60626)(1)

Publication using NBP2-60626

• Fang, Y;Liu, Y;Chen, L;Wang, J;Zhang, J;Zhang, H;Tian, S;Zhang, A;Zhang, J;Zhang, JH;Wang, X;Yu, J;Chen, S; Cerebrospinal fluid markers of neuroinflammation and coagulation in severe cerebral edema and chronic hydrocephalus after subarachnoid hemorrhage: a prospective study Journal of neuroinflammation 2024-09-27 [PMID: 39334416]

FAQs for Coagulation Factor XI ELISA Kit (NBP2-60626). (Showing 1 - 1 of 1 FAQ).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: F11