CLEC10A/CD301 Antibody (ER-MP23) [DyLight 488]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr
Clone
ER-MP23
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 488

CLEC10A/CD301 Antibody (ER-MP23) [DyLight 488] Summary

Immunogen
Balb/c macrophage precursor cell hybrids
Localization
Membrane; Single pass type II membrane protein.
Specificity
NB100-64874 recognizes murine CD301, a 38 kD cell surface protein that is otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR). In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated. Clone ER-MP23 is reported to block the function of mouse CD301. The antibody binds both MGL1 and MGL2 homologues.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CLEC10A
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CLEC10A/CD301 Antibody (ER-MP23) [DyLight 488]

  • CD301 antigen
  • CD301
  • CD301C-type lectin domain family 10 member A
  • CLEC10A
  • CLECSF13
  • CLECSF14
  • CLECSF14macrophage C-type lectin
  • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 14 (macrophage-derived)
  • C-type lectin domain family 10, member A
  • C-type lectin superfamily member 14
  • HML2
  • HMLC-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 13 (macrophage-derived)
  • macrophage lectin 2 (calcium dependent)
  • Macrophage lectin 2
  • MGL

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB100-64874APC
DyLight 350 Labeled NB100-64874UV
DyLight 405 Labeled NB100-64874V
DyLight 680 Labeled NB100-64874FR
DyLight 755 Labeled NB100-64874IR
PE Labeled NB100-64874PE
PerCP Labeled NB100-64874PCP

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Bioinformatics Tool for CLEC10A/CD301 Antibody (NB100-64874G)

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Diseases for CLEC10A/CD301 Antibody (NB100-64874G)

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Pathways for CLEC10A/CD301 Antibody (NB100-64874G)

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Bioinformatics

Gene Symbol CLEC10A
Entrez