Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) - IHC-Prediluted

Immunohistochemistry-Paraffin: Chorionic Gonadotropin beta Chain (hCG beta) Antibody (HCGab/52) - IHC-Prediluted [NBP2-48067] - Human Placenta stained with hCG Monoclonal Antibody (HCGab/52).

• Reactivity: Hu
• Applications: IHC
• Clone: HCGab/52
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: IHC-Prediluted

Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) - IHC-Prediluted Summary

• Description: The prediluted antibody does not require any mixing, dilution, reconstitution, or titration; the antibody is ready-to-use and optimized for staining.
• Immunogen: Purified Chorionic Gonadotropin alpha/beta (hCG) protein
• Localization: Cytoplasmic, Secreted
• Marker: Pregnancy & Choriocarcinoma Marker
• Specificity: This monoclonal antibody is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CGB3
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Hu-chromosome location: 17q21.2
  Immunohistochemistry-Paraffin 0.5 - 1 ug/ml for 30 minutes at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10 - 20 min followed by cooling at RT for 20 minutes. The 7mL size is a pre-diluted size and no additional dilutions are required before using this item for the intended application.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) - IHC-Prediluted

• CGB;CGB3;CGB5;CGB7;CGB8;Choriogonadotropin subunit beta 3;Choriogonadotropin subunit beta 7;hCGB;LHB

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CGB3