Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) [DyLight 405]

• Reactivity: Hu
• Applications: IHC
• Clone: HCGab/52
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 405

Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) [DyLight 405] Summary

• Immunogen: Purified Chorionic Gonadotropin alpha/beta (hCG) protein
• Localization: Cytoplasmic, Secreted
• Marker: Pregnancy & Choriocarcinoma Marker
• Specificity: This monoclonal antibody is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CGB3
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) [DyLight 405]

• CGB;CGB3;CGB5;CGB7;CGB8;Choriogonadotropin subunit beta 3;Choriogonadotropin subunit beta 7;hCGB;LHB

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CGB3