CHORDC1 Antibody [DyLight 405]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit

CHORDC1 Antibody [DyLight 405] Summary

Immunogen
A synthetic peptide made to an internal portion of the human CHORDC1 protein (between residues 100-250) [UniProt Q9UHD1]
Localization
Nucleus. Cytoplasm.
Clonality
Polyclonal
Host
Rabbit
Gene
CHORDC1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Conjugate
DyLight 405
Format
DyLight 405 (A=400, E=420)
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Applications/Dilutions

Dilutions
  • Western Blot 1:2500
  • Immunocytochemistry/Immunofluorescence 1:100-1:400
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150
Application Notes
This CHORDC1 antibody is useful for Western Blot where a band is observed ~37kDa, Immunocytochemistry/Immunofluorescence, and IHC-paraffin embedded sections. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

Reactivity Notes

Human and mouse.

Alternate Names for CHORDC1 Antibody [DyLight 405]

  • CHORD domain-containing protein 1
  • CHORD-containing protein 1
  • CHP1CHP-1
  • cysteine and histidine-rich domain (CHORD) containing 1
  • cysteine and histidine-rich domain (CHORD)-containing 1
  • cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
  • cysteine and histidine-rich domain-containing protein 1
  • FLJ37289
  • Protein morgana

Background

Cysteine and histidine-rich domain containing 1 (CHORDC1; CHP1) is a member of a novel family of highly conserved proteins. These proteins are factors in plant disease resistance, as well as animal development. Mammalian Chp-1 is a novel Hsp90-interacting protein that contains two CHORD domains and one CS domain. CHP-1 binds to the ATPase domain of Hsp90, but this interaction does not utilize ATP and ATPase- coupled conformational change of Hsp90 (PMID: 15642353). High ADP:ATP ratios in cell lysates appears to promote the interaction between CHP1 and Hsp90 (PMID: 19875381). Additionally, CHP-1 has been shown to be 63% homologous to Melusin; a muscle specific protein necessary for heart hypertrophy caused by mechanical burden (PMID12965203).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CHORDC1 Antibody (NBP1-78304V) (0)

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Secondary Antibodies

 

Isotype Controls

Additional CHORDC1 Antibody [DyLight 405] Products

CHORDC1 NBP1-78304V

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Blogs on CHORDC1

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol CHORDC1

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