CEP290 Antibody - BSA Free

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Immunoprecipitation: CEP290 Antibody - BSA Free [NBP3-47642] - IP result of anti-CEP290( for IP and Detection)with HeLa cells.
Western Blot: CEP290 Antibody - BSA Free [NBP3-47642] - HeLa cells were subjected to SDS PAGE followed by western blot with (CEP290 Antibody) at dilution of 1:600
Immunohistochemistry: CEP290 Antibody - BSA Free [NBP3-47642] - Immunohistochemistry of paraffin-embedded human placenta using (CEP290 antibody) at dilution of 1:50
Immunocytochemistry/ Immunofluorescence: CEP290 Antibody - BSA Free [NBP3-47642] - Immunofluorescent analysis of ( -20℃ Ethanol ) fixed HeLa cells using ( CEP290 Antibody) at dilution of 1:50 and Alexa Fluor ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

CEP290 Antibody - BSA Free Summary

Description
Novus Biologicals Rabbit CEP290 Antibody - BSA Free (NBP3-47642) is a polyclonal antibody validated for use in IHC, WB, ELISA, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
centrosomal protein 290kDa. (Uniprot# O15078)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CEP290
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:50-1:500
  • Immunohistochemistry 1:20-1:200
  • Immunoprecipitation 1:500-1:5000
  • Western Blot 1:200-1:2000
Application Notes
Theoretical Molecular Weight is 290 kDa, 150-180 kDa, 80 kDa, 60 kDa

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 50% Glycerol, pH (7.3)
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for CEP290 Antibody - BSA Free

  • BBS14Bardet-Biedl syndrome 14 protein
  • Cancer/testis antigen 87
  • centrosomal protein 290kDa
  • Cep290
  • CT87JBTS6
  • FLJ13615
  • JBTS5CTCL tumor antigen se2-2
  • KIAA0373FLJ21979
  • LCA10monoclonal 3H11 antigen
  • MKS4
  • Nephrocystin-6
  • NPHP6centrosomal protein of 290 kDa
  • POC3 centriolar protein homolog
  • POC3
  • prostate cancer antigen T21
  • rd16,3H11AG
  • SLSN6nephrocytsin-6,3H11Ag
  • Tumor antigen se2-2

Background

CEP290 encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Research Areas for CEP290 Antibody (NBP3-47642)

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Blogs on CEP290.

LAMP2: Protector of the lysosome
LAMP2 belongs to the family of membrane glycoproteins who confer selectins with carbohydrate ligands. LAMP2 has been implicated in tumor cell metastasis, as well as overall protection, maintenance, and adhesion of the lysosome. It appears that LAMP2 m...  Read full blog post.

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Bioinformatics

Gene Symbol CEP290