CENTD1 Antibody

Immunohistochemistry-Paraffin: CENTD1 Antibody [NBP2-23697] - Staining of human cervix tumor tissue using preimmune sera (top) and this antibody (bottom) at 1:50.

Product Discontinued

CENTD1 Antibody Summary

• Immunogen: Within the range of amino acids 78-100 of human ARAP2 protein were used as the immunogen.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ARAP2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50

Reactivity Notes

This antibody detects an approximately 66 kD band in human brain lysate by western blot, but the theoretical molecular weight of JMJD4 is approximately 50 kD. The reason for this size discrepency is not known.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 0.1 ml crude whole Rabbit sera with 50% Glycerol
• Preservative: 0.025% Sodium Azide
• Purity: Unpurified

Alternate Names for CENTD1 Antibody

• Arf and Rho GAP adapter protein 2
• ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
• centaurin, delta 1
• Centaurin-delta-1
• CENTD1arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
• cnt-d1
• FLJ13675
• FLJ44916
• KIAA0580centaurin-delta-1
• PARX
• Protein PARX

Background

CENTD1 is encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. This protein lacks the predicted catalytic arginine in the RHO-GAP domain and is therefore unlikely to have RHO-GAP activity. While the encoded protein does contain a sterile alpha motif (SAM) commonly found in some signaling molecules, the function of the protein has not been determined. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARAP2